Monday, June 30, 2008

Great Weekend


One of my best friends from high school came to visit me in SF last weekend, and we drove to check out Stanford Business School for him before going to an 80s cover band concert on Friday night. The next morning, we biked around the perimeter of Angel Island, which was reachable by ferry and surprisingly lovely. The bike ride took about 1.5 hours, and the best part was how you could get a 360 degree view of San Francisco bay and how each part of the path gave you a slightly different by no less breathtaking view of the colorful houses, blue water, and white sailboats. I liked how the scenic view changed as you labored around the island, the changing nature was perhaps one of my favorite parts. It's weird, I told Leo, how after we visited Alcatraz 2 years ago, that I would not visit Alcatraz more than once, but I would definitely visit Angel Island again.
On Sunday, we visited Napa and tasted wine at Freemark Abbey, Louis Martini (hands down the best cabs in terms of taste & value, all 5 wines were amazing and I couldn't dump a single drop), V Sattui, Mondavi, and Opus One (ridiculous and excellent $30 tasting of one extremely hyped- up wine). We also saw the view from Artesa.
Today in medicine, it made me happy to think that only yesterday I was in Napa. :-)

Thursday, June 26, 2008

Gone Baby Gone II

Learned from a fellow medical student that the baby from my first delivery ever died a few weeks ago. It was a huge jolt, because I never expected the baby to die, even though his Apgars (assigned by me after some review with the peds team) were 3, 4, and 6. I assumed that he was going to make it after watching him for almost 10 hours after he was born, and now he has become my first peds patient to pass away.

Peds vs. Surgery

Notable quotes

...from peds: a boy in clinic with penis pain says that his "peanuts" hurts...Awww!

...from a friend in surgery: a resident who barks, "THERE'S NO TIME FOR TEACHING, ONLY LEARNING."

Saturday, June 14, 2008

Pausch's Last Lecture

Four days of fever, 1 day of sore throat, and 1 day of recovery (6 days total) and I'm back to baseline....wow, that took way longer than expected. :( I'm a little bummed that my 2-week summer vacation was cut in half by a pediatric viral illness, but I'm glad that it happened at a "convenient" time (so to speak) when there was not much going on and no patients to see.

Talking to my roommate made me realize that there are different senses of the word "sick," there's the conversational "sick" when you have sniffles or a mild URI. Then there's the second-level "sick," when you can't get out of bed and feel truly miserable and incapacitated for a short while and remember how much it sucks to not be healthy. There's also "sick" in the sense of mental illness, which is chronic and difficult to describe and quantify, and there's also the profound sense of "sick," usually earning you that "coveted" admission to the hospital because one of your organs is failing, or you need surgery with dorky UC med students watching, or sometimes because you are dying.

Most people on the web have heard of Randy Pausch, PhD, the professor at Carnegie Mellon University dying from pancreatic cancer who gave a stirring "Last Lecture" about life lessons. A few months ago, I learned about him from an interview in Time magazine, but didn't bother to Google his lecture until a friend in pharmacy school told me about it in the laundry room today. You can watch it on Google videos, it's a bit long (76 minutes), but worth the investment.

Naturally, I was interested because Randy is a pancreatic cancer patient, and if you don't read my blog that often, I am interested in pancreatic cancer research. Different cancers have different mortality rates, but pancreatic cancer remains a fearsome predator among cancers with a median survival of 6 months depending on how far the tumor spreads.

Oncology keeps drawing me closer, but still no idea. I told my friend in the laundry room that I'm interested in oncology because it's work that continually reminds me by its very nature why I am working and what really matters in this life. Somehow, by working with pancreatic cancer patients who continually face this duel with death, I feel like oncology motivates me to work even harder and with more purpose. Paradoxically and more importantly, oncology also simultaneously inspires me to appreciate everything non-work related in life -- family, friends, food, food, creature comforts, beautiful moments, holidays, and the ease of health. How can anything else teach me so elegantly to value both work and everything non-work?

Dr. Pausch's video: http://video.google.com/videoplay?docid=-5700431505846055184
Dr. Pausch's homepage: http://download.srv.cs.cmu.edu/~pausch/

Friday, June 13, 2008

Happy Graduation, Matthew!

My little brother Matthew is graduating from Arcadia High School today!
Congratulations, Matthew!
Pictured with his prom date, but don't worry ladies, he's single! (as far as we know)

Wednesday, June 11, 2008

Coxsuckie

Did you know...?

From Wiki: "The Coxsackie viruses were discovered in 1948-49 by Gilbert Dalldorf, a scientist working at the New York State Department of Health in Albany, New York. Dr. Dalldorf, in collaboration with Grace Sickles, had been searching for a cure for the dreaded disease polio. Earlier work Dalldorf had done in monkeys suggested that fluid collected from a non-polio virus preparation could protect against the crippling effects of polio. Using newborn mice as a vehicle, Dalldorf attempted to isolate such protective viruses from the feces of polio patients. In carrying out these experiments, he discovered viruses that often mimicked mild or nonparalytic polio. The virus family he discovered was eventually given the name Coxsackie, for the town of Coxsackie, New York, a small town on the Hudson River where Dalldorf had obtained the first fecal specimens."

There's also a good Wiki clinical description:
"The most well known Coxsackie A disease is hand, foot and mouth disease (unrelated to foot and mouth disease), a common childhood illness which affect mostly children aged 10 or under[1], often produced by Coxsackie A16. In most cases infection is asymptomatic or causes only mild symptoms. In others, infection produces short-lived (7-10 days) fever and painful blisters in the mouth (a condition known as herpangina), on the palms and fingers of the hand, or on the soles of the feet. There can also be blisters in the throat, or on or above the tonsils. Adults can also be affected. The rash, which can appear several days after high temperature and painful sore throat, can be itchy and painful, especially on the hands/fingers and bottom of feet."

It should really be called Coxsuckie!!

Tuesday, June 10, 2008

The Other Foot-in-Mouth Disease

First day of my 2-week vacation and I come down with a 101.8 degree fever, mouth sore, and sore throat.

Today I woke up hoping it would be better, but I'm still sweating enough to fill a small swimming pool, must have caught something from the kiddos in pediatrics. Couldn't make it to my longitudinal clerkship in radiation oncology, but it's probably better not to give a virus to cancer patients getting chemotherapy. Stumbled into Student Health Services (SHS) this afternoon with a fever of 102.6 F, sore throat, apthous ulcer, and slightly bleeding gums. Since I just completed my pediatrics clerkship, my differential included strep throat and hand-foot-and-mouth disease (Coxsackie virus A).

As a kid, I remember getting HFMD with my siblings, and how I thought that it was called "Foot in Mouth Disease," and felt confused because that was supposed to mean something else...

Rapid strep test was negative (but you would still order a culture if your suspicions were strong), and the doctor said it was probably HFMD. The disease lasts 7-10 days (good use of vacation, eh?), and includes fever, sore throat, oral ulcers, and itchy vesicles on your hands and feet. Not all presentations have the full hand-foot-mouth thing.

My fever has been running pretty high these past 3 days, and i've been doing some reading on the internet to see if tylenol vs. motrin (ibuprofen) is better as a fever reducers. Some studies say ibuprofen, some say alternating both drugs works best.

Monday, June 09, 2008

Heal Thyself

Came down with a 101.7 F fever last night...must have caught something from the kiddos. I sat on the couch for a good 20 minutes before I realized, "Hey, I could be taking an antipyretic right now." So I took Tylenol, but at the clinic we always give feverish kids ibuprofen, I wonder which one works better for fevers. Another useful thing that I learned in peds is that fevers burn off a lot of water, so you have to rehydrate mucho -- and that dehydrated kids will decompensate a lot faster and with less warning than adults do.

Woke up this morning with a fever of 101.8 F...Arghhh.

Wednesday, June 04, 2008

My First Peds Patient in WBN

Baby Sierra (with permission)

Tuesday, June 03, 2008

Cancer Stem Cell Symposium

Recently found out that I missed a cancer stem cell symposium at UCSF...bummer.

http://cancer.ucsf.edu/symposium2008/

Monday, June 02, 2008

Education > Contraception

On adolescents: "An increase in the number of years of schooling for a woman delays the age at which a woman marries and has her first child."

Seriously?

What about men?

Smegma

Attendings throw around the word "smegma" occasionally in clinic, and I assumed that it was a slang term for secretory accumulations of "schtuff," but apparently it's an actual scientific term. Mmm, gross!

From Wikipedia:
"Smegma, a transliteration of the Greek word σμήγμα for sebum, is a combination of exfoliated (shed) epithelial cells, transudated skin oils, and moisture, and can accumulate under the foreskin of males and within the vulva of females. It has a characteristic strong odor. Smegma is common to all mammals, male and female. Mycobacterium smegmatis is the characteristic bacterium involved in smegma production, and is generally thought to form smegma from epidermal secretions."

Sunday, June 01, 2008

Anti-Babies

Intern: "Baby M and Baby M2 are the anti-babies...don't put them together or they'll explode."

Saturday, May 31, 2008

Bye Bye Baby

Babies are born into this world into different situations, and while most babies are born into loving families, the range of parents is amazing. Some parents have special "birth plans" and pediatrician appointments already established before the baby even leaves the hospital, while other babies need Child Protective Services (CPS) because the mom's living situation is unsafe or unstable.

Baby M was a small baby girl born during my second day of service in the newborn nursery, the daughter of a mom who told Jim, the intern, that she had used drugs, smoked a pack a day, and injected an IV "speedball" (cocaine and heroine) during her pregnancy. The situation was not unusual, but it naturally made the hospital staff a little concerned. Dad was in prison, mom was acting a little strange, and it was unclear whether mom would be able to take care of Baby M.

CPS offered to check mom into a residential rehab facility so that she could live with her baby, but mom was upset about not being able to take care of a dog at home. Since mom's urine tox tested positive for methamphetamines, and so did Baby M's, the staff decided to keep the baby in the nursery until mom detoxed a little. Usually, babies stay with their moms in the hospital rooms in order to promote bonding. Gone are the days when u see babies lined up in little rows behind a glass window, the newborn nursery is usually a quiet place when no circumcisions are occurring (just kidding).

Jim, the compassionate intern, urged that Baby M stay with mom to encourage bonding. Maybe spending time with her baby would convince mom to take CPS's offer of a second chance. Disappointingly, mom didn't seem to be interested in taking care of Baby M...who spent the same amount of time in the nursery as before.

Whenever we saw Baby M -- small, quiet, with a rounded nose -- sleeping in her crib alone in the newborn nursery -- I would look at Jim with a funny expression and he would shrug his shoulders at me with an air of disappointment. Jim really cared about Baby M.

On Friday, Baby M's mom was discharged from the hospital. CPS informed her that Baby M was going to be taken into foster care, but the full impact of the news seemed to escape her and she left.

It was quiet in the nursery that Friday afternoon. It was getting late -- 5 p.m. -- and people were leaving for home and the weekend. The sun was growing dimmer over a spectacular 15th floor view of San Francisco and the only occupant in the newborn nursery was quiet little Baby M waiting to be picked up by the foster care program at 6 p.m. Her eyes were open, but she was silent, so I picked her up and rocked Baby M in my arms for a few minutes to say good-bye. As I thought about how all of the other babies in the ward had gone home with happy families and all of the love and opportunity that awaited these other babies -- tears started coming to my eyes thinking about how Baby M was left behind in the hands of strangers.

When Baby M's mom dramatically returned to the newborn nursery the next afternoon -- glassy tears streaming down her face because she couldn't find her baby in the Well Baby Nursery or anywhere in the hospital -- it was hard not to feel sorry for a mom wearing dirty tennis shoes with rolled down socks and a red sweatshirt who didn't realize -- like many of us -- what she had lost until it was truly gone.

My First C-Section (as a med student)

The pager beeped and we dropped everything and ran to the labor and delivery room.

After a week of waiting, I finally witnessed my first newborn delivery. The mom was Rh negative and sensitized to Rh factor (which is sort of like seeing an ivory-billed woodpecker because everyone has read about it, but few people have seen such a case in the U.S. now that we are so meticulous about managing pregnant moms), and the baby was Rh positive.

The Ob-Gyn docs tried to pull the baby out using forceps, but baby wasn't coming out...so they took mom to the OR to do a C-section. I saw my first C-section, which was eerily how I imagined it. Save your romantic notions that surgery is a delicate scientific process...they made a transverse incision across mom's lower belly and reached in to grab the baby. There was a fair amount of blood, but it was fascinating how much of the blood was collected by a plastic bag around the incision (will learn more about this later, hopefully), and the tough Ob-Gyn ladies were pulling and rummaging around mom's belly looking for the blue baby. The pediatrics team generously allowed me to hold a blue sterile towel so that I could "catch" the baby. Soon we could see the head, and the Ob-Gyn attending reached in and pulled the baby out of the womb by its head. I held my arms outstretched, holding the blue cloth, ready to receive the baby from the Ob-Gyn docs, and the baby landed in my arms, newly severed from mom -- a big blue baby that was sort of floppy and doll-like. I carried the baby 3 feet to a warmer and we began warming, drying, and vigorously stimulating the baby with towels...he had Apgar scores of 3, 4, and 6.

The baby was taken to the ICN and I watched as the residents put in a central line. I mentioned that it was my first delivery, and one of the residents asked if I was keeping a journal of my third year of medical school. I told him no, but I do keep a blog...

Working in the Well Baby Nursery this week (or Hell Baby Nursery according to some interns who dislike the loads of paperwork, the MS3's LOVE the nursery) was a lot of fun. It was very pleasurable playing with newborns, they are so different from any other patients and a pleasure to care for. The parents are always very excited and grateful, and the dads are amusingly awkward and sort of dazed and eager to help. I learned how to perform a newborn exam, and what things to look out for and what findings are normal in a newborn.

Thursday, May 22, 2008

Medicine and Domestic Violence

Sent by a JMP student today...

May 20, 2008

Screening for Abuse May Be Key to Ending It

By ERIN N. MARCUS, M.D.

The silver-haired woman greeted me at the clinic door, one arm suspended in a bright blue sling.
This wasn’t her first visit. In the preceding few months, she had come to the clinic twice with assorted aches and inexplicable pains. Now her husband had broken her arm, and the reason for those visits had become glaringly obvious: he had been hitting her.

And the domestic violence screening question I’d asked months before — nestled between queries about smoking and seat belts — seemed to have been spectacularly ineffective, since she’d answered “no.”

When I had asked about violence at home, I had been following guidelines set by the surgeon general and many professional groups, including the American Medical Association. Those who support routine questioning say domestic violence is as or more common in women than many diseases for which doctors regularly check, including breast and colon cancer, and its health risks are well documented.

Despite these recommendations, screening for domestic abuse in seemingly healthy women is nowhere near as widespread among doctors as testing for breast cancer or high cholesterol.
Some physicians see domestic violence primarily as a criminal justice issue, and take umbrage at being expected to delve into a difficult, messy topic when they already have to screen for many other conditions and diagnose complicated diseases in the span of an ever-shorter visit.
In a recent nationwide study of nearly 5,000 women, only 7 percent said a health professional had ever asked them about domestic or family violence. When surveyed, doctors often respond that they don’t ask such questions because of a lack of time, training and easy access to services that help these patients.

Some have reported that they worry about offending patients and believe asking won’t make any difference.

“Just like anybody else, doctors avoid things they may have discomfort doing,” said Dr. Michael Rodriguez, a researcher and family practitioner at the University of California, Los Angeles.

“There’s also an expectation on the part of some folks that once we identify abuse she should just walk away, and frustration when she doesn’t.”

Dr. Rodriguez and other experts say that urging an abused patient simply to leave may not be realistic or safe, for several reasons: The risk of being murdered is highest at the time one leaves, the woman may depend on her partner for food and shelter, and patients may not respond well to a doctor who dictates what to do.

They also say the best way to ask about such abuse is in a private place, with no family members present, as part of the routine patient history. If the patient says she has been battered or threatened at home, experts recommend that the doctor offer empathy, tell her what’s happening is wrong, document her story in the medical record and provide her with information on places to go or refer her to someone who may be able to help, like a social worker.
Barbara Gerbert, director of the Center for Health Improvement and Prevention Studies at the University of California, San Francisco, said that while some women might deny domestic violence at first, the question itself could have a profound effect: many women remember that their doctor asked and eventually, even years later, reveal their secret.

“Just by asking, you may be planting a seed for change,” she said.

Numerous studies indicate that doctors ask about domestic violence poorly, however, and don’t handle it well when they do get a yes answer.

Felicia M. Frezell, 34, an office manager in Omaha, told me recently that she visited her doctor’s office many times with her five children during the 15 years she lived with her ex-husband, who was convicted in 2005 of raping her. She said that even though she often had bruises, no one ever asked her why — until she asked her doctor to look at her swollen black eye and told him her husband had hit her.

“He just said, ‘You’d better get out of that situation’ and left it at that,” Ms. Frezell said, and added: “Looking back, I didn’t know the resources that were out there. The doctor’s office is a good place to go because it’s neutral and it’s confidential. It’s not like telling your husband you’re going to the police department.”

According to the Bureau of Justice Statistics, from 2001 to 2005 (the last year for which statistics are available) there was an annual average of nearly 511,000 violent assaults against women — and 105,000 against men — by a spouse or intimate partner, about half resulting in physical injury.

Despite such numbers, the United States Preventive Services Task Force concluded in 2004 that although clinicians should “be alert” for signs of violence, there was insufficient evidence to recommend for or against screening asymptomatic patients for domestic abuse — mainly because of a dearth of large-scale scientific studies looking at this question.
While many researchers say more money is needed to pay for such studies, some say the analogy to routine screening misses the point.

“Trying to equate it to a Pap smear is the wrong paradigm, and it’s just irrelevant,” said Dr. Christina Nicolaidis, a general internist and researcher at Oregon Health and Science University. “It’s not a test you can just check off.”

“The reasons to ask,” she continued, “are to educate a patient and to open the door so that the patient knows she can come to you. It’s part of developing a real relationship with your patient. Over time, you might be able to uncover the abuse and improve her safety, but you also might better understand why she’s having her symptoms and how to better approach her self-management of her illness.”

Abused women are at increased risk of chronic pain, depression, anxiety and alcohol and substance abuse, and they can have problems taking their medication correctly and getting to appointments. In one recent study, women who said they had been abused within the past year were more likely to have partners who interfered with their medical care.

Seven years ago, the Institute of Medicine, which advises the federal government, issued a major report on the training of health workers on family violence. The report concluded that such violence “was not a consistent priority” in health workers’ education and recommended that the Department of Health and Human Services establish education and research centers in family violence.

By unhappy coincidence, the report was unveiled at a news conference on Sept. 11, 2001, and has since “collected dust,” said one of the authors, Felicia Cohn, who now directs medical ethics at the University of California, Irvine.

“Certainly other issues took precedence at the time,” Dr. Cohn added, “but the continuing inattention is both inexcusable and embarrassing. This is a public health pandemic with immense health care implications.”

For my silver-haired patient — and other women I see at the clinic where I work — there have been no simple answers. I keep the telephone numbers for a local women’s shelter and the police department’s domestic violence unit in my lab coat pocket. And I keep asking the question, so my patients know there’s a place they can turn.

Erin N. Marcus is a general internist and associate medical director of the Institute for Women’s Health at the University of Miami Miller School of Medicine.

Monday, May 19, 2008

Finger to Nose

Just got back from the ED (for some reason, the med community calls it the ED, while the public calls it the ER or emergency room).

Pediatric urgent care was crazy busy today (everyone waits until Monday over the weekend), was there until 8 p.m. Then went over to the ED and saw the cutest 4 y/o boy with an eyelid laceration because his friend hit him in the eye with a rusty pole this afternoon (me: "it doesn't sound like he's a very good friend").

The cutest thing was when I was doing the neuro exam to make sure that his brain was intact after getting whacked in the head, and I asked him to do finger-to-nose to test his coordination.

Me: "Okay, I want you to touch your nose and then touch the tip of my finger."
Boy: [Sticks his index finger up his nostril to the first knuckle and withdraws a snot-covered finger]
Me: [Collective "Eew" arises from adults watching. Me pulling finger away quickly while parents burst out laughing] "Heh...okay...um, let's test your other finger..."

Wow, I never expected that from a pediatric finger-to-nose exam!

On another note, I am so far removed from current events...Robert Mondavi passed away and apparently there was this big earthquack in China. For a great blog posting on Anderson Cooper 360, please refer to a posting written by the sister of my former housemate: http://ac360.blogs.cnn.com/2008/05/19/china-children-searching-for-their-parents/#comments

Shit, did I just say "earthquack"?

Thursday, May 15, 2008

Thoughts on Parents

In college, I was most interested in pediatrics because a) I like kids; b) I have 3 younger siblings whose ages range over a 12-year span; and c) most of my community service in high school and college reflected working with little kids or mentoring adolescents.

Feeling comfortable with babies, toddlers, preteens, teenagers has helped me enjoy my pediatric rotation, so it's funny how by the end of my year finishing clinical research at Stanford, my career interests had changed course and my interest in oncology grew. As a patient population, I really enjoyed working with an older age group of patients who had pancreatic cancer -- they had diverse backgrounds, interests, and personalities tied together by an unfortunate and often tragic illness.

One thing that worried me about pediatrics was the hearsay that it's not just the patient whom you have to worry about...but often their neurotic and demanding parents who are understandably worried about their most precious charges. Hearing that argument, I was turned off by the idea that maybe I could not treat the patient directly, but would spend much of my time negotiating diagnoses and treatments by proxy. Another common argument one often hears is that pediatrics can sometimes be "veterinary medicine" (I don't like this phrase), since nonverbal children cannot articulate their symptoms or discomfort.

During my pediatrics rotation, I have found that my worries about Parents (with a capital P) have been exaggerated. Although some Parents can be bossy, demanding, and overly histrionic, I have more often found myself touched by the love, dedication, and sacrifice that each parent demonstrates for his or her child. An infant who received a liver transplant practically lives in our inpatient ward with his parents and older brother, who spend every hour with him, sleeping on chairs and air mattresses every night and never leaving his side for days without a word of complaint or resentment. A mom who cries because her son has anorexia and will not eat anything she offers. Another mom asking about the cognitive effects of whole brain irradiation on her 10 y/o son with Down's syndrome and ALL. Parents who take showers in the hospital, sleep on chairs every night, pour every ounce of energy into supporting their children, no matter how sick the child is or how hopeless the situation may be.

So now I find that Parents tug at my heartstrings as much as their children do, and everything that I have always loved about kids remains the same. Children perceive the world differently, they are more pure of heart and have cute miniature body parts.

Adolescents are an interesting age group, too, they have such a unique set of concerns, risk factors, and half-formed perceptions of the world and how it should be. At best, their preoccupations and insecurities amuse and touch me, at worst, their teenage angst and myopic, self-conscious and self-centered views of the world impede effective medical care.

Overall, however, both pediatric patient groups demonstrate an acute vulnerability that makes me want to take care of them, and their little Parents too.

Wednesday, May 14, 2008

Pediatric Urgent Care

Today, I diagnosed a 16-month-old girl with acute otitis media. I am proud of this because a) the baby couldn't tell me what was hurting her and b) i've never seen an inflamed TM before. This makes me feel like maybe someday I can be a semi-competent doctor.

I also helped take care of a 10 y/o boy today who fell on his head and had a 2.5 cm. forehead laceration that was so deep it was down to the bone. It was a really wicked cool laceration, and the poor boy took it like a champ. Watching the suturing was so cool!

There was also a 4 y/o girl who also fell on the pavement, but she presented with waxing and waning mental status and 3 bouts of emesis in the exam room. We rushed her to the CT scanner in the emergency department to check her head.

Saturday, May 10, 2008

Random Peds Quotes

Intern: "Can't trust a four-year-old."

Intern: "Why don't we do pregnancy tests on all of our male adolescents, too? It would be more thorough and less discriminatory."

"The longer you stay...the longer you stay." (this makes so much more sense now that I'm in the hospital than it did before)

Senior: "She's afebrile and non-edematous, which is...weird."

Senior: "She's going to barf on you."